A downloadable game for Windows, macOS, and Linux

Buy Now$2.99 USD or more

A microscopic world is in need of your help! Add transporters to membranes to move molecules and ions into and out of cells. Your goal is to reach specific concentrations.

 Over 20 unique puzzles will help you master the principles of cellular transport. Use channels, co-transporters, and antiporters to master facilitated diffusion and active transport.

 Think you understand how transporters diffuse molecules and ions across the membrane? Try making your own puzzles with the built in level editor!


  • Over 20 puzzles ranging from a gentle introduction to challenging mind benders.
  • Speed up and slow down time to play at your own pace.
  • 16 transporters including real proteins found in your body and imaginative nano-robots.
  • Puzzle mechanics based on real biological principles of cellular transport.
  • Built-in level editor lets you take control and make your own levels to challenge your friends!
Published Apr 19, 2017
PlatformsWindows, macOS, Linux
Release date Apr 28, 2017
AuthorCogent Education
GenrePuzzle, Educational
TagsLevel Editor, Mouse only, Touch-Friendly
Average sessionA few minutes
InputsMouse, Touchscreen, Smartphone
LinksSteam, Homepage, Steam Greenlight, Twitter


Buy Now$2.99 USD or more

In order to download this game you must purchase it at or above the minimum price of $2.99 USD. Your purchase comes with a Steam key. You will get access to the following files:

Against the Gradient for Windows Version release-15-ge363916 29 MB
Against the Gradient for MacOS Version release-15-ge363916 32 MB
Against the Gradient for Linux Version release-15-ge363916 40 MB

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